Hokkaido University Research Profiles

Japanese

Rheumatoid arthritis: 1

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  • Rheumatoid AI Diagnostic Research

    Simple photographic assessment of joint space narrowing

    We will attempt to develop a consulting system that provides objective and detailed quantitative analysis information on destructive joint changes in rheumatoid arthritis patients. The image analysis will be measured based on changes in X-ray images over time using a program we had developed, and the information will be provided to research and clinical institutions in Japan and overseas.

    Research

    We have been developing and validating software to objectively measure the progression of joint space narrowing on plain x-rays. The latest software, using our original temporal subtraction and contour extraction techniques, is capable of displaying changes (in square millimeters) in the area of the joint space of the target limb.
    On the other hand, even from a global perspective, it is difficult to automatically detect the progression of joint space narrowing on plain x-rays using software, and the process still partially relies on manual operation, making it impossible to perform measurement at individual hospitals or clinics. Therefore, the purpose of this study is to establish an internet-based consulting system for quantitative analysis of destructive changes due to rheumatoid arthritis that can meet the needs of domestic and international clients who lead clinical trials and clinical research.